Synthesis, characterization and antimicrobial activity of a new 1,3-bis(4-fluorophenyl)-5-butyl-1,3,5-triazacyclohexane

Authors

  • Amel Ferhati aboratory of Analytical Sciences Materials and Environment, Faculty of Exact Sciences and Sciences of Nature and Life, Larbi ben M'Hidi University, 04000 Oum El Bouaghi, Algeria b Laboratory of Applied Chemistry and Materials Technology LCATM, Faculty of Exact Sciences and Sciences of Nature and Life, Larbi ben M'Hidi University, 04000 Oum El Bouaghi, Algeria
  • Samira Malki Laboratory of Applied Chemistry and Materials Technology LCATM, Faculty of Exact Sciences and Sciences of Nature and Life, Larbi ben M'Hidi University, 04000 Oum El Bouaghi, Algeria
  • ahcene Bouchemma Laboratory of Applied Chemistry and Materials Technology LCATM, Faculty of Exact Sciences and Sciences of Nature and Life, Larbi ben M'Hidi University, 04000 Oum El Bouaghi, Algeria
  • Leila Lefrada Laboratory of Analytical Sciences Materials and Environment, Faculty of Exact Sciences and Sciences of Nature and Life, Larbi ben M'Hidi University, 04000 Oum El Bouaghi, Algeria b Laboratory of Applied Chemistry and Materials Technology LCATM, Faculty of Exact Sciences and Sciences of Nature and Life, Larbi ben M'Hidi University, 04000 Oum El Bouaghi, Algeria
  • Wissam Mazouz Department of Biology, Faculty of Science, Badji Mokhtar University, 2300 Annaba, Algeria
  • Mustapha Bouhenguel Laboratory of Applied Chemistry and Materials Technology LCATM, Faculty of Exact Sciences and Sciences of Nature and Life, Larbi ben M'Hidi University, 04000 Oum El Bouaghi, Algeria

Keywords:

triazacyclohexanes, formalin, butylamine, antimicrobial activity;, condensation

Abstract

n this paper, a new hexahydrotriazine derivative which have the structure 1,3-bis(4-fluorophenyl)-5-butyl-1,3,5-
triazacyclohexane was synthesized by the condensation reaction of a 1 :2 :1 ratio, 4-fluoroaniline and butylamine with
formalin in a basic solution. The synthesized compound was characterized by elementary analysis and spectroscopic
methods IR, UV, mass spectroscopy, 1
H and 13
C NMR.
The new triazacyclohexane has been screened for its antimicrobial activity against Gram positive and Gram negative bacteria
by the diffusion on agar medium.

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Published

2025-01-06

How to Cite

Ferhati, A., Malki, S., Bouchemma, ahcene, Lefrada, L., Mazouz , W., & Bouhenguel , M. (2025). Synthesis, characterization and antimicrobial activity of a new 1,3-bis(4-fluorophenyl)-5-butyl-1,3,5-triazacyclohexane. Journal of New Technology and Materials, 9(02), 17–21. Retrieved from http://review.univ-oeb.dz/ojs.jntm/index.php/jntm/article/view/127

Issue

Vol. 9 No. 02 (2019)

Section

Articles

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